Sumatriptandosage

For subcutaneous use only

Acute treatment of migraine: single dose of 1 to 6 mg

Acute treatment of cluster headache: single dose of 6 mg

Maximum dose in a 24-hour period: 12 mg, separate doses by at least 1 hour

Patients receiving doses other than 4 or 6 mg: Use the 6-mg single-dose vial

2.1 Dosing Information

The maximum single recommended adult dose of Sumatriptan injection, USP for the acute treatment of migraine or cluster headache is 6 mg injected subcutaneously. For the treatment of migraine, if side effects are dose limiting, lower doses (1 mg to 5 mg) may be used. For the treatment of cluster headache, the efficacy of lower doses has not been established. The maximum cumulative dose that may be given in 24 hours is 12 mg, two 6 mg injections separated by at least 1 hour. A second 6-mg dose should only be considered if some response to a first injection was observed.

2.3 Administration of

Doses of Sumatriptan Other than 4 or 6 mg In patients receiving doses other than 4mg or 6 mg, use the 6-mg single-dose vial; Visually inspect the vial for particulate matter and discoloration before administration. Do not use if particulates and discolorations are noted.