Isotretinoininteractions
isotretinoin 25 MG Oral Capsule
This is the interactions section of this product’s FDA label — what the manufacturer documented for this drug. It is not a check of your medication list, and a drug missing from it has not been cleared: licensed clinical databases list far more interactions than any single label does. Before combining medicines, ask a pharmacist, who can check everything you take at once and will do it for free.
Named on this label
Every name above is printed in the text below. This is not the full set of drugs that interact with this one — it is the set this manufacturer wrote down.
Drug interactions
Vitamin A: avoid concomitant use Tetracyclines: avoid concomitant use
7.1 Vitamin A
Avoid concomitant use of isotretinoin with supplements containing vitamin A. Isotretinoin is closely related to vitamin A. Therefore, concomitant use of isotretinoin with vitamin A may lead to isotretinoin-associated adverse reactions.
7.2 Tetracyclines
Avoid concomitant use of isotretinoin with tetracyclines because isotretinoin use has been associated with a number of cases of intracranial hypertension (pseudotumor cerebri), some of which involved concomitant use of tetracyclines.
7.3 Oral Contraceptives
Isotretinoin Capsules did not result in clinically significant changes in the pharmacokinetics of norethindrone and ethinyl estradiol when used concomitantly with a norethindrone and ethinyl estradiol oral contraceptive. It is not known if there is an interaction with the concomitant use of isotretinoin with other oral contraceptives.
Text above is quoted in full from the FDA-approved drug label published by openFDA, effective June 4, 2025. Matched to this product by RxNorm code. Cross-references to other sections of the full prescribing information have been removed, since they point to a document not shown here. Nothing else is changed: no sentence is shortened, reworded or summarised.
This page reproduces regulatory text for reference. It is not medical advice, and KenyRx is not a pharmacy or a prescriber. Talk to a doctor or pharmacist about whether a medicine is right for you.
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