Eluxadolinedosage

The recommended dosage of VIBERZI is 100 mg taken orally twice daily with food. The recommended dosage of VIBERZI is 75 mg taken orally twice daily with food in patients: unable to tolerate the 100 mg dose of VIBERZI. receiving concomitant OATP1B1 inhibitors. with mild (Child-Pugh Class A) or moderate (Child-Pugh Class B) hepatic impairment. with moderate or severe renal impairment (eGFR less than 60 mL/min/1.73 m 2 ); and in patients with end stage renal disease (ESRD) not yet on dialysis (eGFR less than 15 mL/min/1.73 m 2 ). Discontinue VIBERZI in patients who develop severe constipation. Instruct patients if they miss a dose, take the next dose at the regular time and not to take 2 doses at the same time to make up for a missed dose. The recommended dosage in adults is 100 mg twice daily taken with food. The recommended dosage is 75 mg twice daily taken with food in patients: unable to tolerate the 100 mg dose. receiving concomitant OATP1B1 inhibitors. with mild or moderate hepatic impairment. with moderate or severe renal impairment; and in patients with end stage renal disease not yet on dialysis. Discontinue VIBERZI in patients who develop severe constipation. If a dose is missed, take the next dose at the regular time; do not take 2 doses at once.