Dexmethylphenidatedosage

Administer orally twice daily, 4 hours apart with or without food. For patients new to methylphenidate: Recommend starting dose of 5 mg once daily (2.5 mg twice daily). For patients currently taking methylphenidate: Initiate dexmethylphenidate hydrochloride tablets therapy with half (1/2) the current total daily dose of methylphenidate. Titrate weekly in increments of 2.5 to 5 mg to a maximum of 20 mg/day (10 mg twice daily).

2.1 Pretreatment

Screening Prior to treating patients with dexmethylphenidate hydrochloride tablets, assess: for the presence of cardiac disease (i.e., perform a careful history, family history of sudden death or ventricular arrhythmia, and physical exam). the family history and clinically evaluate patients for motor or verbal tics or Tourette’s syndrome before initiating Dexmethylphenidate hydrochloride tablets.

2.2 Recommended

Dosage Patients New to Methylphenidate The recommended starting dose of Dexmethylphenidate hydrochloride tablets for pediatric patients who are not currently taking racemic methylphenidate, or for patients who are on stimulants other than methylphenidate, is 5 mg daily (2.5 mg twice daily) with or without food. Patients Currently on Methylphenidate The recommended starting dose of dexmethylphenidate hydrochloride tablets for pediatric patients currently using methylphenidate is half (1/2) the total daily dose of racemic methylphenidate. Titration Schedule The dose may be titrated weekly in increments of 2.5 to 5 mg to a maximum of 20 mg daily (10 mg twice daily). The dose should be individualized according to the needs and response of the patient.

2.3 Administration

Instructions Dexmethylphenidate hydrochloride tablets is administered orally twice daily, at least 4 hours apart.

2.4 Dosage Reduction and

Discontinuation If paradoxical aggravation of symptoms or other adverse reactions occur, reduce the dosage, or if necessary, discontinue dexmethylphenidate hydrochloride tablets. If improvement is not observed after appropriate dosage adjustment over a one-month period, the drug should be discontinued.