acetaminophencost and price(30 Count)
acetaminophen 500 MG / diphenhydramine hydrochloride 25 MG Oral Tablet
Used for
Allergic perennial rhinitis, Anxiety disorders, Fever, Hives, Motion sickness, Nausea, Pain, Sleep initiation and maintenance disorders and 1 more
Pain reliever Nighttime sleep aid · NLM RxClass and the FDA drug label
What it cost pharmacies
CMS NADAC benchmark
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Over the counter
You may not need a pharmacy for this at all.
acetaminophen 500 MG / diphenhydramine hydrochloride 25 MG Oral Tablet is sold over the counter. The prices below are what pharmacies pay to dispense it on a prescription — the same active ingredient is on the shelf at a supermarket, discount store, or dollar store, usually as a store brand, for a small fraction of that. Dollar Tree, Aldi, Walmart and Costco all carry store-brand versions of common OTC medicines.
Check the strength before you switch. Prescribed strengths are often higher than what is sold on a shelf — the shelf box may be a lower dose per tablet, so you would not be taking the same thing at 30 count. Ask your pharmacist or prescriber to confirm the shelf product matches what you were prescribed.
Where to buy
HealthWarehouse
- Drug cost (30 Count)
- $4.51
- Per-order fees
- $5.00
- Pharmacies paid
- $1.32
- Markup on the drug
- +241.7%
free shipping on prescriptions and on OTC orders over $15; otherwise $5 standard
12 × 30 count at $9.51. That is a year of fills at this pack size — check your own prescription for how often you actually need it.
Ordered alongside other medication so the per-order fee is shared: $54.12/year
These prices are what we found when we last checked, on November 1, 2026. They can change by the time you reach the pharmacy, and sales tax may apply. Not medical advice.
HealthWarehouse
- Drug cost (30 Count)
- $4.51
- Per-order fees
- $5.00
- Pharmacies paid
- $1.32
- Markup on the drug
- +241.7%
free shipping on prescriptions and on OTC orders over $15; otherwise $5 standard
12 × 30 count at $9.51. That is a year of fills at this pack size — check your own prescription for how often you actually need it.
Ordered alongside other medication so the per-order fee is shared: $54.12/year
Still too expensive?
Manufacturer programmes cover many uninsured people, often for nothing. A few questions about income and insurance — none of it stored.
Also listed under
Taken from what this drug's own FDA label lists it for, and the pharmacologic class it is assigned. Each one prices every other drug we hold in it.